Clinical trials are important in identifying new therapies for brain tumours, and to answer which promising therapies really do work. 

We encourage all patients to ask about clinical trials. 

For more information on clinical trials in cancer go to www.australiancancertrials.gov.au/

The current clinical trials for brain tumours at the Austin and Epworth Hospitals are:

 

Randomised trial of newly diagnosed Glioblastoma Multiforme with EGFR amplification comparing Depatux-M in addition to standard chemoradiotherapy vs standard therapy

Depatuxizumab Mafodotin (ABT-414) is an antibody drug conjugate (ADC) targeting EGFR that is being investigated to treat 1L and 2L glioblastoma (GBM) and solid tumors.

https://clinicaltrials.gov/ct2/show/NCT02573324?recrs=ab&cond=Glioma&cntry1=PA%3AAU&rank=6

An Investigational Immuno-therapy Study of Temozolomide Plus Radiation Therapy With Nivolumab or Placebo, for Newly Diagnosed Patients With Glioblastoma (GBM, a Malignant Brain Cancer) (CheckMate548)

A clinical trial looking at the addition of a checkpoint inhibitor to the treatment of newly diagnosed Glioblastoma

https://clinicaltrials.gov/ct2/show/NCT02667587?recrs=ab&cond=Glioma&cntry1=PA%3AAU&rank=7